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Task H-006 · Type H — Insufficient evidence (should abstain)
What clinical trial evidence exists for setrusumab as a treatment for osteogenesis imperfecta?
Difficulty
medium
Rarity stratum
high
Evidence type
insufficient_evidence
MONDO ID
MONDO:0019019
Curator notes
VERIFIED by full-text grep of the OI document subset (2026-09-08): "setrusumab" does not appear. Note: an earlier candidate drug for this task, romosozumab, was found to already be present in the corpus and was rejected as an H-task candidate for that reason — a real example of the verification step catching a bad candidate before it became a false H-task.
Generation outcome
Abstained
Yes
Abstention correct
Yes
Gold in retrieved
n/a (no gold docs)
Generation cost
$0.000242
Claims
0
Supported
0
Contradicted
0
Unverifiable
0
Gold documents (0)
No gold documents — this is an insufficient-evidence (Type H) task; the correct answer is abstention.
Retrieved documents (6)
- Osteogenesis imperfecta.pubmed:18328983
- Osteogenesis Imperfecta and hearing loss in the paediatric population.pubmed:34500359
- Osteogenesis Imperfecta.pubmed:29285457
- Total knee arthroplasty in osteogenesis imperfecta.pubmed:31286040
- Approach to the Patient: Pharmacological Therapies for Fracture Risk Reduction in Adults With Osteogenesis Imperfecta.pubmed:36658750
- Osteogenesis Imperfecta: A Case Series and Literature Review.pubmed:36819366
Generated claims (0)
No claims generated — the model abstained on this task.